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Broncos vs. Jaguars score predictions for Week 2

Ahead of their Week 2 clash in Denver, the Jacksonville Jaguars arrive with a 1-0 record to face a 0-1 Denver Broncos squad. Jacksonville enters the contest having prevailed in the previous meeting between the franchises during Week 15 on December 21, 2025, when they handed Denver a 34-20 defeat as the sole visiting team to conquer Empower Field at Mile High that year.

Denver quarterback Bo Nix, who completed a second-quarter touchdown throw in that prior matchup, now aims to reverse fortunes against a Jacksonville attack led by signal-caller Trevor Lawrence. Meanwhile, the Jaguars look to maintain offensive momentum under coordinator Liam Coen as both sides prepare for Sunday's encounter.