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2026 College Football Week 5: Best Games To Watch This Weekend

College football fans and bettors have a heavy slate of matchups to monitor in Week 5, starting with undefeated Alabama hitting the road to face Mississippi State. The Crimson Tide are coming off a dominant 49-18 win over South Carolina, while the Bulldogs enter after a 31-24 victory against Missouri.

In another major clash, Ohio State looks to maintain momentum against a top-25 Iowa defense following wins over Kent State and Illinois. Meanwhile, Florida puts its 4-0 record and high-scoring offense on the line against Missouri, and USC tries to bounce back from an Oregon loss when hosting Washington at the Coliseum.

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Use DraftKings promo code to land $150 in bonus bets by targeting Washington-USC, Miami-Clemson on Saturday