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First-year wide receiver Skyler Bell was ruled inactive despite being uninjured as the Buffalo Bills traveled to face the Houston Texans for their opening contest of the 2026 campaign. Buffalo enters the matchup attempting to secure its first victory on Houston's home turf since 2006, as both playoff teams from the previous season clash in an early-season AFC showdown featuring quarterbacks Josh Allen and C.J.
Stroud.
The visiting roster was already tested by depth concerns prior to kickoff, managing three players listed as questionable alongside the possibility of activating practice squad personnel. Meanwhile, questions surrounded the availability of Keon Coleman and Will Anderson Jr.
on the respective injury reports leading up to the Sunday opener.

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