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NFL Week 4 betting: 5 biggest storylines, including Bucs adjustment with backup QB and Rams' Super Bowl odds

Following a week where the top five most heavily backed wagers all delivered for gamblers at BetMGM, attention now shifts to the fourth slate of games. The Buccaneers face a major adjustment as Baker Mayfield is forced to miss at least three weeks due to a thumb dislocation, leaving undrafted rookie Jalon Daniels to command the offense.

Meanwhile, despite a sluggish 1-2 start, the Rams share the shortest championship odds with the Bills across several major sportsbooks, showing that oddsmakers are unwilling to discount Los Angeles just yet.

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