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                        Will Brinson's NFL Week 1 predictions and picks: Best bets, player props, anytime TD scorers for Sunday
NFL

Will Brinson's NFL Week 1 predictions and picks: Best bets, player props, anytime TD scorers for Sunday

September 13, 2026

Week 1 wagering analysis highlights advantageous spots across Sunday's NFL slate, pointing to home underdogs Indianapolis and Houston as appealing options while projecting Jalen Hurts and Philadelphia to successfully cover the spread against Washington. Although game totals are mostly being bypassed to open the year, spread selections, individual player propositions, and anytime touchdown wagers present prime targets.

Among the featured matchups, Arizona stands out as a 9.5-point underdog versus the Chargers, with the spread dropping beneath double digits after sitting in the mid-teens earlier in the offseason. Cardinals quarterback Jacoby Brissett enters the contest backed by receiving weapons Trey McBride, Marvin Harrison Jr., and Michael Wilson, while running back Tyler Allgeier is slated to share rushing duties with Jeremiyah Love if the latter is cleared to play.

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