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                        Week 4 NFL odds, picks, predictions: Computer model backs Giants and Seahawks
Photo via CBS Sports
NFL

Week 4 NFL odds, picks, predictions: Computer model backs Giants and Seahawks

October 3, 2026

Ahead of the upcoming slate of professional football matchups, an advanced prediction system has completed ten thousand computer simulations for every fixture on the schedule. The upcoming slate includes an international contest in London featuring the Indianapolis Colts giving four and a half points against the Washington side, while Jayden Daniels sits out due to an elbow injury.

Other notable point spreads feature the Baltimore group favored by eleven and a half points over the winless Tennessee squad, and the Minnesota representatives giving ten points against Miami. Additionally, the New Orleans franchise enters Monday night as two and a half point favorites over Atlanta, marking the twentieth anniversary of the Domecoming celebration from two thousand six.

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