Photo via CBS Sports

NFL Week 2 injury report: Lions down two starting offensive lineman vs. Bills, including Blake Miller

Ahead of their Thursday evening showdown against Buffalo, Detroit faces significant depth issues along their offensive front. Starting right tackle Blake Miller is sidelined due to a knee problem, while starting left guard Christian Mahogany will also sit out with a hip ailment.

J. Reed, who carries a questionable tag because of a foot concern.

J. Sanders, rusher Ty Johnson, and safety Cole Bishop as questionable, following restricted practice sessions on Wednesday.

Injuries continue to mount across the league heading into the second week of action. J.

Brown have shifted to injured reserve, while quarterback Sam Darnold is slated to miss his upcoming matchup with a soft tissue issue. J.

Terrell on Wednesday, whereas Carolina held out Bobby Brown III and Patrick Jones II while Jalen Coker managed limited work on an injured ankle.