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Caleb Williams has surged back into the NFL MVP betting conversation, with his odds tightening to +500 following a strong showing against Seattle. The Bears quarterback had previously drifted to 55-1 while sidelined by a hamstring injury.
Meanwhile, Justin Herbert has been removed from the MVP board entirely after the Chargers opened their season with seven consecutive losses, while Patrick Mahomes has seen his MVP odds lengthen to 17-1 despite leading the race for Comeback Player of the Year at -150. In other award races, Jaxon Smith-Njigba has climbed to +260 for Offensive Player of the Year, trailing Jahmyr Gibbs, who is currently the favorite at +155.
Will Anderson Jr. remains the frontrunner for Defensive Player of the Year at +230, though Jeffery Simmons has seen his odds improve to 10-1 after a successful first game with Chicago following his trade from Tennessee.

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