Photo via CBS Sports

Missouri State vs. Western Kentucky CFB odds Thursday: Hilltoppers should end 4-game skid against FBS foes

Western Kentucky’s four-game losing streak against FBS opponents ends Thursday when Missouri State visits Houchens Industries Stadium for a Conference USA showdown. The Hilltoppers, who entered the season as preseason favorites in CUSA, are desperate to break their skid after four straight losses—each by at least 21 points—while averaging a 36-point margin of defeat.

Despite their recent struggles, WKU remains one of only nine FBS programs with at least eight wins in each of the past five seasons, a feat that includes back-to-back trips to ranked Georgia and Indiana. Missouri State, meanwhile, is riding a 0-3 start and must win to remain in contention for the CUSA Championship, currently priced as a +900 longshot to reach the title game for the first time since 2024.

The game kicks off at 7 ET on CBS Sports Network, with the Hilltoppers favored at -135 on the money line and the over/under set at 56.5.

Up nextCollege Football· 42m ago

Texas steals 4-star RB commit previously committed to Oklahoma right before rivalry game