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College football Week 5 best bets: 7 spread picks after major line movement

Week 5 college football betting analysis highlights several intriguing matchups, including Penn State visiting Northwestern on Friday night at the newly opened stadium. The Nittany Lions aim to bounce back under their first-year coach following a narrow home loss, while relying on a dominant defensive unit that surrenders very few points per game.

Meanwhile, Michigan seeks recovery after a heartbreaking final-play defeat, facing a Minnesota squad coming off a strong road victory against Washington anchored by a productive passing performance and a fierce pass rush.

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