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College football odds, lines, schedule for Week 10: No. 1 Miami opens as road underdog at Notre Dame

Week 10 of college football delivers a slate packed with high-stakes matchups, starting with a potential playoff elimination showdown in the SEC. Alabama, ranked No.

10, will face No. 15 LSU in Baton Rouge, where the Crimson Tide have dominated recently, but LSU’s home-field advantage is offset by quarterback Keelon Russell’s struggles in his last outing.

Meanwhile, the ACC’s top rivalry heats up as No. 5 Notre Dame welcomes No.

1 Miami in a primetime clash, with the Fighting Irish opening as slight 4.5-point underdogs. Both teams have shown recent vulnerabilities—Notre Dame lost to BYU, while Miami’s secondary was exposed in a narrow win over North Carolina.

Elsewhere, Ohio State remains a heavy favorite against Oregon, Utah seeks to extend its lead in the Big 12 by hosting BYU in the Holy War, and Georgia looks to extend its dominance over Ole Miss at home.

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