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Use FanDuel promo code to get $350 in bonus bets for Bills vs. Lions on NFL Thursday Night Football

Thursday Night Football for Week 2 of the 2026 NFL campaign features an interconference showdown between the Buffalo Bills and the Detroit Lions, with start time scheduled for 8:15 p.m. ET.

Buffalo opens as a 5.5-point home favorite at the new Highmark Stadium, while sportsbooks have pegged the projected total at 54.5 points. Jared Goff guides a potent Detroit attack managed by Dan Campbell that includes playmakers Amon-Ra St.

Brown, Jahmyr Gibbs, and Jameson Williams, going head-to-head against a Buffalo offense led by quarterback Josh Allen.

SportsLine's computer simulation system, carrying a 53-39 record on highest-rated selections dating back to 2024, backs the total to eclipse 54.5 with a 56 percent probability. In the player proposition market, Buffalo receiver D.J.

Moore faces a receiving threshold of 63.5 yards following a 100-yard outing against Houston in the opener; the predictive formula anticipates Moore will collect just 44.4 receiving yards and gives the under on that yardage total a 4.5-star grade. Meanwhile, new FanDuel registrants can secure $350 in promotional wagers by putting down at least $5 across seven consecutive days.

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