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NFL Week 2 picks: Our experts face off on Lions at Bills Thursday night, Bengals vs. Texans and more

5. Both franchises match the Philadelphia Eagles for the league's top record since 2023 at 37-15, and Buffalo is inaugurating the new Highmark Stadium, where entry tickets reached approximately $400 on Ticketmaster.

While Detroit boasts an NFL-best 14-3 record in primetime over the previous five seasons, Buffalo has claimed five consecutive victories over the Lions and won 10 of their last 12 home games in primetime. 7 passing yards per meeting, which includes an NFL-record defeat in which he posted 400 yards, five passing touchdowns, and zero interceptions.

J. Stroud.

Analysts anticipate offensive contributions from Buffalo's Josh Allen, James Cook, DJ Moore, and Dalton Kincaid, alongside Detroit's Goff, Amon-Ra St. Brown, and Jameson Williams, leading to a projected 36-30 Bills triumph.