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Week 5 NFL odds, picks, predictions: Computer model backs Vikings and Bengals

The SportsLine predictive algorithm has completed 10,000 simulations for the upcoming Week 5 NFL slate. The model, which has maintained a profitable track record since its launch, currently favors the Minnesota Vikings and Cincinnati Bengals in its latest projections.

As the league enters its first week of scheduled byes, the betting landscape features a marquee matchup between the Seattle Seahawks and San Francisco 49ers, with Seattle opening as a three-point home favorite. Other notable lines include the Houston Texans facing the Tennessee Titans as seven-point underdogs, the Pittsburgh Steelers hosting the Indianapolis Colts with a 2.5-point spread, and the Miami Dolphins entering their contest against Cincinnati as 7.5-point underdogs.

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