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Washington vs USC Prediction: Odds, expert picks, team and player news, betting trends, and stats

Both eighteenth-ranked USC and Washington head into their upcoming Week 5 matchup seeking a rebound following tough defeats. The Trojans suffered a 41-27 primetime setback against Oregon, whereas the Huskies dropped a 27-24 decision to Minnesota during a late-night contest.

Saturday night's showdown at Los Angeles Memorial Stadium will feature head coach Lincoln Riley guiding USC against Washington with kickoff scheduled for 7:30 PM Eastern on NBC and Peacock. DraftKings lists the Trojans as 8.5-point favorites with an over-under set at 58.5 points, while the moneyline stands at -360 for USC and +285 for Washington.

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