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USC vs. Washington Picks, Odds, Parlay for College Football Week 5

Eleventh-ranked USC returns to action on its home field following a disappointing defeat against Oregon, preparing to host Washington for a Big Ten showdown on Saturday evening. The Trojans currently sit as 9.5-point favorites while their opponents enter the matchup as +300 road underdogs.

USC quarterback Jayden Maiava leads the nation with 1,499 passing yards and 14 touchdowns through four games, supported by true freshman receiver Kayden Dixon-Wyatt. Meanwhile, Washington counters with dual-threat quarterback Demond Williams Jr. following a narrow home loss to Minnesota.

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