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TST Best Bets: September 26, 2026

Saturday features a pair of high-stakes Big Ten matchups, starting with twelfth-ranked USC hosting twentieth-ranked Oregon at the Coliseum as the Trojans attempt to halt a four-game skid in the rivalry. Oregon enters following an 84-0 rout of Portland State, while USC looks to tighten up a defense that surrendered 35 points to Rutgers last week, making the over on 61.5 an attractive option.

In the second featured showdown, seventeenth-ranked Iowa puts its unbeaten record on the line against eighteenth-ranked Michigan in Ann Arbor. Given the Wolverines' recent offensive inconsistencies and the Hawkeyes' strong historical record against the spread when facing ranked opponents, experts recommend taking Iowa plus the 5.5 points in what projects to be a tightly contested affair.

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