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Titans vs. Eagles opening odds

The Tennessee Titans stumbled out of the gate to begin their 2026 campaign, dropping their home opener 23-10 against the New York Jets at Nissan Stadium on September 13. The defeat spoiled head coach Robert Saleh's franchise debut at the hands of his former club, despite Tennessee debuting fresh uniforms under a general manager entering his second year.

Quarterback Cam Ward, who was brought down by defender Will McDonald IV during the final period, expressed frustration with the offensive showing, calling for greater accountability and pledging immediate progress to keep the squad's championship hopes intact.

Looking ahead to Week 2, early betting lines have established the visiting Philadelphia Eagles as significant favorites over Tennessee. The Titans hope to rebound quickly following an uninspiring inaugural weekend that drew jeers from the home crowd.