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Picking every Big Ten game in college football Week 5

College football fans are gearing up for a packed weekend as Week 5 brings eight total conference matchups across the Big Ten. Analysts have projected victories for several prominent programs, including Penn State against Northwestern, Michigan over Minnesota, and Ohio State defeating Iowa.

Additional predictions favor Wisconsin against Michigan State, Nebraska over Maryland, and Illinois topping Purdue.

Further projections for the weekend slate point to USC securing a win against Washington under coach Lincoln Riley, alongside Indiana prevailing against Rutgers as the defending champions aim to push their record to 5-0. Meanwhile, Northwestern is set to debut its brand new stadium while hosting Friday's conference opener.

The full schedule highlights crucial early-season tests for every participating program in the league.

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