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Colts-Commanders opening odds: The Colts are coming!
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NFL

Colts-Commanders opening odds: The Colts are coming!

September 28, 2026

The Indianapolis Colts have finally snapped a nine-game losing skid following a victory in Berlin, and oddsmakers at FanDuel Sportsbook favor them by 3.5 points in their upcoming European matchup against the Washington Commanders. The point spread comes with a money line set at -180 and an over/under opening at 47.5, as both squads aim to reach the .500 mark after rebounding from identical 0-2 beginnings.

During their previous outings, the Colts relied on a stout defensive effort to stifle C.J. Stroud before sealing the win with a long field goal, while Marcus Mariota stepped in for the Commanders to throw three touchdowns in place of Jayden Daniels to defeat the Seahawks.

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