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Week 7 college football odds, storylines: Best bets for Ohio State-Indiana and Saturday's other big games

Week 7 of college football arrives with a slate of pivotal matchups, where underdog victories and coaching missteps have reshaped the playoff picture. Oklahoma’s stunning 40-point rout of No.

1 Texas in the Red River Rivalry cemented their status as a dark-horse contender, now listed at +375 to secure a College Football Playoff berth. Meanwhile, UCLA’s path to the top 12 brightened after Oregon’s offensive struggles—including a baffling 2-point conversion attempt and a season-ending injury to star quarterback Dante Moore—left the Bruins poised for a playoff push, especially if they can navigate the Rose Bowl showdown with USC.

The Trojans’ own quarterback, Nico Iamaleava, faces an indefinite absence, adding another layer of uncertainty to the Pac-12 title race. Beyond the Power Five, Kentucky’s late-game resilience continues to dominate headlines, as their overtime wins have left LSU with two losses and a shrinking chance to avoid a playoff miss, now priced at -250 to fall short.

South Carolina’s late-season surge also gained momentum with a dominant win over Florida, further isolating the Gators as the most likely SEC team to collapse under playoff pressure, now at -1000 to avoid the CFP entirely. The SEC’s top two teams, Georgia and Alabama, remain locked in their championship chase, with the Bulldogs’ narrow edge over the Crimson Tide in Week 6 underscoring the razor-thin margins defining this season’s elite.

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