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Score Prediction: Indiana Hosts Ohio State In Big Ten Blockbuster
Photo via Yahoo Sports
College Football

Score Prediction: Indiana Hosts Ohio State In Big Ten Blockbuster

October 17, 2026

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The Big Ten delivers one of its most anticipated showdowns of the season as No. 5 Indiana welcomes No.

4 Ohio State to Bloomington for a high-stakes clash with major playoff implications. The Hoosiers, currently undefeated and defending their home turf, will look to maintain their dominance after handing the Buckeyes their first loss since 1988 in a December meeting.

Ohio State, seeking redemption and a statement win, arrives with a roster brimming with talent but faces the challenge of overcoming Indiana’s stifling defense—a unit that has already forced the Buckeyes into costly turnovers and limited their offensive firepower in past matchups. With both teams ranked in the top five nationally, the victory will carry significant weight in the conference standings and the College Football Playoff race, adding to the pressure for both programs.

Analysts and models have flagged this game as a potential turning point, particularly for Ohio State, which has already suffered an unexpected loss earlier this season and cannot afford another setback on the road.

Up nextCollege Football· 49m ago

Don’t buy the hype: Why Ohio State is in trouble at Indiana

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