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NFL Week 4 odds: Eagles open as home underdogs to the Rams
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NFL

NFL Week 4 odds: Eagles open as home underdogs to the Rams

September 29, 2026

Following a difficult loss to the Chicago Bears, the Philadelphia Eagles prepare for their upcoming Week 4 contest at Lincoln Financial Field as three-point home underdogs against the Los Angeles Rams. Oddsmakers and historical trends note that the franchise has struggled significantly against the spread when hosting as home underdogs since the start of the current era in 2021.

Despite recent difficulties, the franchise holds a strong historical record against this opponent, winning ten out of eleven matchups since 2005 and four consecutive meetings against Sean McVay since 2023. Meanwhile, the visiting team enters the weekend holding a one-and-two record following earlier defeats to the San Francisco 49ers and the Denver Broncos.

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