Justin Herbert throws one TD, one INT in Week 1

The Los Angeles Chargers suffered an unexpected 26-14 defeat against the Arizona Cardinals to begin their 2026 NFL campaign. Heavy favorites entering the matchup under head coach Jim Harbaugh and offensive coordinator Mike McDaniel, Los Angeles struggled to find an offensive rhythm against an Arizona squad helmed by quarterback Jacoby Brissett.

The Cardinals showcased an overhauled coaching staff that adjusted quickly, stifling the Chargers throughout the contest.

Despite the disappointing outcome, Justin Herbert managed to surpass the 25,000 career-yard milestone after needing just 180 yards coming into the day. The Los Angeles signal-caller finished the contest tallying 209 total yards, finding the end zone once through the air while also tossing a single interception.

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Caleb Downs has no injury designation, George Pickens listed as questionable