The San Francisco 49ers' already depleted wide receiver corps suffered another setback Sunday night when star WR Deebo Samuel exited the second half of their NFC West showdown at Seattle with a hamstring injury. The loss compounds a season of misfortune for the position group, which has seen key contributors Ricky Pearsall (out for the year after PCL surgery) and rookie sensation De’Zhaun Stribling (sidelined until at least Week 10 with a deltoid tear) also ruled out.
With over 15 players on the injured/reserve list—including defensive linemen Alfred Collins and Sam Okuayinonu, as well as cornerback Nate Hobbs—the 49ers entered the game already shorthanded, and Samuel’s departure further eroded their offensive depth against a Seahawks defense. The injury marks the latest blow to a unit that had already lost two more receivers to questionable status before kickoff, leaving quarterback Brock Purdy with limited options downfield in a critical divisional clash.

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