49ers star Nick Bosa uncovers injury timeline as NFC West clash for first place approaches

October 10, 2026

San Francisco 49ers defensive end Nick Bosa remains on track to return from a calf strain by Week 6, though he will miss Sunday’s critical NFC West showdown against the defending Super Bowl champion Seattle Seahawks. The star pass rusher, who has sat out his last two games, will not travel with the team to Seattle and plans to stay in the Bay Area for focused rehab, aiming to rejoin practices next week.

Bosa’s timeline hinges on his progress, with his coaching staff expressing optimism about his potential return for the Oct. 19 home game against the Washington Commanders—or at worst, the following week against the Atlanta Falcons.

Despite his absence, the 49ers’ front office has praised Bosa’s early-season impact, though he has yet to record his first sack of 2024.

Injury concerns extend beyond Bosa, as wide receiver Mike Evans—who played through broken ribs last week against Denver—faces another high-stakes test in Sunday’s game. Though Evans suited up for the Broncos contest despite medical advice, he was limited in Friday’s practice and remains uncertain for the Seahawks matchup.

The 49ers’ undefeated start hangs in the balance, with both Bosa and Evans critical to their playoff push in a division where every game counts.