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What are the odds? LSU sitting as 48.5-point favorites in their Week 5 matchup vs. McNeese State
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College Football

What are the odds? LSU sitting as 48.5-point favorites in their Week 5 matchup vs. McNeese State

September 30, 2026

The eleventh-ranked LSU Tigers return to their home stadium this weekend to host the McNeese State Cowboys for a Week 5 contest. Oddsmakers currently list the home team as massive 48.5-point favorites with an over-and-under line of 61.5 points.

LSU enters this matchup sitting at three wins and one loss following a definitive 35-6 triumph against Texas A&M. Meanwhile, the visiting Cowboys carry a two-and-three record into the contest after narrowly defeating East Texas A&M 27-24 last week.

Head coach Lane Kiffin and the Tigers are looking to build offensive consistency, though quarterback Sam Leavitt's availability remains uncertain due to a leg and hamstring injury sustained in the previous game, with backup Landen Clark ready if needed. McNeese brings momentum from an offensive output that generated 412 total yards, featuring a long touchdown run by Omiri Wiggins and quarterback Jake Strong filling in under center to throw for 202 yards and a score.

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