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Top Big 12 football games to watch in Week 6 during Colorado's bye

Week 6 in the Big 12 delivers a slate of high-stakes matchups that could reshape playoff hopes, with BYU and Iowa State locked in a clash after the Cyclones’ surprising win over West Virginia. Meanwhile, Houston—ranked in the AP poll—takes on Kansas State in a game where the Cougars, despite their 4-1 record, could pull off an upset against the favored Wildcats, who recently lost to Cincinnati.

The conference’s marquee matchup, however, is Arizona versus West Virginia, where two evenly matched teams seek to avoid another conference loss. West Virginia’s run-heavy offense, featuring two backs with over 570 rushing yards, will clash with Arizona’s explosive passing attack, led by quarterback Noah Fifita, who has already amassed over 1,400 passing yards.

Oklahoma State also looks to stay undefeated in conference play with a showdown against UCF, while Utah is heavily favored against Kansas. Arizona State, meanwhile, faces Hawaii in a non-conference game where the Sun Devils are expected to dominate by multiple possessions.

Five teams—Baylor, Cincinnati, Colorado, TCU, and Texas Tech—sit out this week during their bye.

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