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The 49ers have 2 new additions to Wednesday’s injury report

Head coach Kyle Shanahan provided a comprehensive injury update on Wednesday, listing several players who will miss practice, including James Thompson Jr., Nick Bosa, Mike Evans, Dre Greenlaw, Trent Williams, Keion White, Christian McCaffrey, and KhaDarel Hodge. Meanwhile, Romello Height and Mykel Williams were marked as limited participants in Wednesday's session.

Williams is slated to miss Week 4 but targets a Week 5 return, while Shanahan expressed optimism about Dante Pettis stepping up amid receiver shortages and noted that Brandin Cooks is quickly mastering the playbook.

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