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Raiders Week 2: Meet the Chargers

Following an unexpected season-opening defeat at the hands of the Arizona Cardinals at SoFi Stadium, the Los Angeles Chargers are shifting their focus to an AFC West showdown in Week 2. Despite quarterback Justin Herbert leading the roster alongside play-caller Mike McDaniel and head coach Jim Harbaugh, Los Angeles suffered an opening upset against a Cardinals squad embarking on the Mike LaFleur era that featured running back Jeremiyah Love.

The defeat came after a 2025 campaign that saw the Chargers reach the postseason.

Meanwhile, the Las Vegas Raiders enter the matchup having secured a Week 1 victory, putting them atop the division standings. Even with those contrasting opening outcomes, oddsmakers have pegged the Raiders as 7.5-point underdogs heading into their clash against Los Angeles.