Thursday Night Football features an early-season clash between the Detroit Lions and the Buffalo Bills, with both squads entering the contest with 1-0 records. The meeting marks the inaugural regular-season NFL fixture to take place at the newly built Highmark Stadium.
Buffalo heads into the home showdown following a 36-31 triumph over the Houston Texans to start their 2026 campaign. That opening victory was powered by quarterback Josh Allen, who accounted for four touchdowns on the day.
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