The opening game of the wild card round features the fifth-seeded Chicago squad visiting the fourth-seeded San Diego team, separated by a slim two-game gap in the regular season standings. Chicago holds an advantage from their head-to-head meetings, securing five victories in six tries, powered by a massive twenty-three to three blowout on July first.
On the mound, Chicago relies on Matthew Boyd, who compiled ten wins against five losses and a 3.91 earned run average across twenty-two starts, showing strong road splits despite prior struggles against this opponent. San Diego counters with Michael King, who led their rotation with thirty-two starts and a 3.21 earned run average, taking the ball at their home ballpark where every game of this series takes place.

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