Photo via CBS Sports

Colts vs. Commanders odds, picks, predictions: NFL London Game start time, betting preview, best bets

Football fans in the UK are gearing up for an early Sunday matchup overseas as the Indianapolis Colts prepare to clash with the Washington Commanders at Tottenham Hotspur Stadium. Bookmakers currently favor Indianapolis by 4.5 points, while oddsmakers have set the over under line for total points at 46.5.

Washington enters the contest navigating changes under center after injuries affected their quarterback lineup, though Marcus Mariota steps in to lead an aerial attack featuring targets like Terry McLaurin and Stefon Diggs. Both squads have struggled defensively early in the season, ranking among the bottom tiers of the league in yards and points surrendered per contest.

Up nextNFL· 18m ago

Jaguars vs. Bengals odds, picks, prediction, spread, line: NFL Week 4 start time, preview, best bets