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Broncos vs. Seahawks odds, prediction, betting preview, start time: Thursday Night Football picks, best bets

The Seattle Seahawks and Denver Broncos will clash on *Thursday Night Football* in a rematch of their 2014 Super Bowl showdown, aiming to extend their momentum into Week 6. Both teams sit at 3-2 on their records, but their paths to this matchup differ: Seattle lost narrowly to the San Francisco 49ers last week, while Denver overcame a late deficit to defeat the Chargers.

The Seahawks, coming off a three-point loss, are favored by 2.5 points on the road, with the over/under set at 40.5. Meanwhile, the Broncos have defied expectations this season, becoming the first team since the 1981 Bengals to start 3-2 or better despite trailing by at least seven points in the second half in all five games.

The game kicks off at 8:15 p.m. ET at Empower Field at Mile High, where the Seahawks will look to avoid becoming the first defending champion to start the season 3-3 or worse since the 2022 Rams.

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