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49ers vs. Cardinals: How to watch, game time, and betting odds

The San Francisco 49ers enter Week 3 with a strong record after defeating the Los Angeles Rams and Miami Dolphins, but they face a tough matchup against the Arizona Cardinals while managing several key injuries. Defensive standout Nick Bosa is sidelined with a calf injury sustained during pregame warmups, joining wide receiver Demarcus Robinson on the injury list alongside other roster absences.

Meanwhile, the Cardinals are looking to bounce back following a Week 2 loss to the Seattle Seahawks, despite missing safety Dadrion Taylor-Demerson and coping with injuries to quarterback Jacoby Brissett and cornerback Will Johnson. Fans can tune in to Fox for the afternoon broadcast featuring Kevin Kugler and Daryl Johnston on the call.

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