
San Francisco head coach Kyle Shanahan provided a comprehensive injury update on Monday. Kyle Juszczyk is sidelined for two to three weeks with a knee hyperextension, while Marques Sigle faces a multi-week absence due to a high ankle sprain, with Malik Mustapha set to fill his position.
Upton Stout is currently day-to-day regarding a shoulder injury, potentially opening a spot for Ephesians Prysock. Deommodore Lenoir and Jack Jones saw defensive shifts during Sunday's action.
Regarding other roster developments, Nate Hobbs is nearing a return, and Mykel Williams is cleared for team drills with hopes of playing against Seattle this Sunday. Nick Bosa and James Thompson Jr.
are not expected to suit up for that matchup. Christian Kirk remains slated for a Week 6 practice return, while Mike Evans successfully navigated his recent rib issue without further complications.

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