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2026 Week 4 NFL odds, schedule, start times: Bills-Patriots, Cowboys-Texans, Raiders-Chiefs, every other game

The upcoming Week 4 slate of professional football games features an early international matchup in London between the Indianapolis Colts and the Washington Commanders on October 4, 2026. Several marquee rivalries highlight the Sunday schedule, including the Dallas Cowboys facing the Houston Texans, the New England Patriots battling the Buffalo Bills, and the Kansas City Chiefs meeting the Las Vegas Raiders.

The weekend action concludes with a primetime matchup where the Carolina Panthers host the Detroit Lions on Sunday Night Football.

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