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Week 1 NFL picks, predictions for Kalshi, Polymarket, ProphetX: Giants-Cowboys, Packers-Vikings markets

m. ET between the Dallas Cowboys and New York Giants.

Dallas has dominated the rivalry lately, taking nine out of the prior 10 contests. 57 to eclipse 250 passing yards.

Meanwhile, a 10,000-simulation projection system from SportsLine—which boasts over $7,000 in profit for $100 bettors on elite picks historically and entered the week on a 47-32 hot streak since 2024—has evaluated the slate.

Another featured divisional clash showcases the Green Bay Packers meeting the Minnesota Vikings on Sunday afternoon. While Green Bay holds the historical advantage at 67-61-3, Minnesota has secured victories in six of their last 10 encounters.

Following a 9-8 record during the 2025 campaign, the Vikings added former top overall draft selection Kyler Murray during the offseason to take over their quarterback duties.