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Texans vs. Colts predictions, NFL picks, start time: Use Polymarket promo code CBSSPORTS for $50 bonus

Both the Houston Texans and the Indianapolis Colts are searching for their initial victory of the season as they prepare to face each other in Week 3. Both squads enter the matchup with matching 0-2 records following difficult early-season losses.

Quarterback C.J. Stroud leads the Houston offense after throwing for 627 yards through the first two weeks, while quarterback Daniel Jones and running back Jonathan Taylor power the Indianapolis attack following a narrow overtime defeat against Kansas City.

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