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Steelers vs. Patriots picks, odds, prediction: Betting preview, start time and more for NFL Week 2 matchup

The New England Patriots return home to Gillette Stadium on Sunday, September 20, 2026, to host the Pittsburgh Steelers for an NFL Week 2 matchup. m.

5. The Patriots are looking to rebound from a 13-10 season-opening road defeat against the Seattle Seahawks where quarterback Drake Maye threw three interceptions and was sacked three times.

Meanwhile, the Steelers arrive after capturing a 20-13 victory against the Atlanta Falcons in their Week 1 outing. New England finished the previous regular season at 14-3 before falling 29-13 in the Super Bowl, while Pittsburgh secured the AFC North title with a 10-7 record prior to a Wild Card loss to the Houston Texans.

J. Brown due to a high ankle sprain, leaving coach Mike Vrabel's squad to navigate the early portion of the schedule.