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Prisco's Week 2 NFL picks: Rams rout Giants; Chargers, Patriots, Cowboys bounce back

Pete Prisco enters Week 2 following a strong opening slate where he posted a 12-4 record straight up and went 9-7 against the spread. Looking ahead, he anticipates bounce-back performances across the league, forecasting the Chargers to rebound from a home defeat against the Cardinals by topping the Raiders.

Among his specific game forecasts, Prisco projects the Jaguars to defeat the Broncos, while the Falcons are tipped to edge the Panthers 21-17 behind heavy usage of running back Bijan Robinson.

Elsewhere on the Sunday slate, Prisco envisions the Bears besting Carson Wentz and the Brian Flores-led Vikings defense in a 30-24 home victory. Chicago enters that matchup after a dominant Week 1 offensive display against Carolina.

Meanwhile, following their win over the Commanders, the Eagles are projected to comfortably handle the Titans 30-13, capitalizing on Tennessee's struggles following an opening loss to the Jets.