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Prisco's Week 1 NFL picks: Bills end skid vs. Texans, Packers edge Vikings

Week 1 NFL predictions are underway, featuring projections for several intriguing matchups. 5 points against the visiting Atlanta Falcons, who enter with Tua Tagovailoa leading the offense amid quarterback questions and two key edge rushers sidelined.

Opposing him is Aaron Rodgers embarking on his last campaign, positioning the Steelers for a projected 27-17 victory backed by strong defensive play. 5-point favorite Ravens against the Indianapolis Colts, where Lamar Jackson's revamped offensive unit is anticipated to prevail in a high-scoring 34-27 battle.

5-point favorites against the Houston Texans, attempting to snap a six-game losing streak on Houston's home turf. J.

Stroud into turnovers and secure a narrow 23-20 triumph. Beyond these matchups, the opening slate also forecasts Patrick Mahomes directing a victory over the Denver Broncos, while the Green Bay Packers are tipped to edge out the Minnesota Vikings.