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NFL Week 2 picks and score predictions: Bills top Lions in Thursday shootout, Seahawks suffer shocking loss

The opening week of the NFL schedule delivered unprecedented chaos across the league, punctuated by victories from the Raiders, Jets, Giants, and Cardinals—a quartet that had never previously started 1-0 in the exact same campaign. 3 million in survivor pool stakes, while Atlanta found itself perched atop its division without a victory or a quarterback, the Rams dealt with the fallout of traveling to Australia, and Cleveland already looked doomed for postseason contention.

Attention now shifts toward Week 2, headlined by a Thursday night showdown between 1-0 squads as Detroit visits Buffalo. The matchup serves as the regular-season debut for the Bills' brand-new venue, which faced heavy scrutiny during an exhibition trial run last month when hundreds of season-ticket holders discovered blocked sightlines to the playing surface.

m. ET—might even have to resort to watching the broadcast on their mobile devices if their seats suffer from identical viewing obstacles.