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How to bet on 2026 NFL Week 1: Betting guide, odds, trends, game previews, schedule, promo codes, more offers

The 2026 NFL opening week features a busy 13-game Sunday lineup, highlighted by clashes between Houston and Buffalo, Minnesota and Green Bay, as well as New York hosting Dallas. 5 points.

Sunday Night Football at MetLife Stadium sees John Harbaugh make his head coaching debut with the Giants against Dak Prescott, who enters his tenth campaign directing the Dallas offense. 5-point total.

5-point favorites over the reigning division champion Broncos. The contest marks Patrick Mahomes' return to the field following a nine-month recovery from a major knee injury.

C. and Puerto Rico, with prominent operators such as DraftKings, FanDuel, and BetMGM providing special promotional incentives for the start of the regular season.