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2026 Week 5 college football odds, betting lines, spreads, start times: Get CFB predictions, best bets, picks

College football fans and bettors are preparing for the upcoming Week 5 slate, which features nearly sixty games spanning Thursday through Saturday. Major matchups include Mississippi State taking on Alabama, Iowa meeting Ohio State, and Missouri facing Florida.

Various sportsbooks are offering sign-up promotions and bonus bets for users wagering on these contests.

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