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2026 Week 3 NFL odds, lines, start times, schedule: Picks, predictions for Broncos-Rams, every other game

Week 3 of the NFL season brings a slate filled with injury updates and betting lines. Giants quarterback Jaxson Dart faces a potential season-ending knee injury, putting Jameis Winston in line to start against the Titans.

Meanwhile, Seahawks coach Mike Macdonald reports that Sam Darnold is progressing well from a glute injury, whereas Commanders quarterback Jayden Daniels deals with an elbow issue ahead of their matchup.

In other Week 3 action, the Bills head into a contest against the Chargers following a 41-31 victory where Josh Allen tallied five touchdowns and James Cook III rushed for 135 yards. The Chargers are looking to rebound from an 0-2 start after a loss to Las Vegas in which Justin Herbert threw a pair of interceptions and Omarion Hampton gained 94 yards on the ground.

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