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2026 Week 2 NFL odds, betting lines, spreads, start times: Get Week 2 NFL picks, predictions for every game

Ahead of the 15 remaining fixtures in Week 2 of the 2026 NFL campaign, oddsmakers have established point spreads for several key matchups. 5 points against the Minnesota Vikings.

5-point edge over the Indianapolis Colts.

The Chiefs enter their showdown with Indianapolis after securing a comfortable win against the Denver Broncos. Sportsbooks have set the total over/under for that Kansas City-Indianapolis game at 46.5 points.