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2026 Week 2 NFL odds, betting lines, spreads, start times: Get Week 2 NFL picks, predictions for every game

Week 2 of the NFL calendar delivers a 16-game slate loaded with significant early-season betting angles. 5 points.

5-point favorites versus the Washington Commanders.

5. Both franchises enter following dramatic Week 1 triumphs: Detroit edged the New Orleans Saints 31-30 in overtime, while the Bills emerged with a 36-31 road victory against Houston.

Later on Sunday afternoon, Aaron Rodgers and the Pittsburgh Steelers are scheduled to square off against the New England Patriots.