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2026 NFL Week 3 early odds: Eagles road favorites vs. Bears after Caleb Williams injury; Broncos home dogs

Following a chaotic Week 2 that resulted in multiple injuries across the league, early point spreads for Week 3 have shifted significantly. Caleb Williams and Jayden Daniels both sustained physical setbacks, causing their respective squads to lose substantial ground with oddsmakers.

The Chicago Bears transitioned from slight favorites to heavy underdogs against Philadelphia, while the Washington Commanders are now catching six points at home against Seattle. Elsewhere on the slate, Green Bay prepares to host Atlanta on Thursday night as a seven-point favorite following an overtime escape against the Jets at MetLife Stadium.