Photo via Yahoo Sports

What the Bills first injury report of the week really tells us.

Following an opening-week victory over the Houston Texans, the Buffalo Bills issued an estimated Monday workout log featuring six members as they ready for a Thursday night encounter with the Detroit Lions. Buffalo's defensive depth chart faces immediate scrutiny with both Terrel Bernard and Cole Bishop surfacing on the latest medical ledger.

The visiting Lions are managing their own physical setbacks, particularly across the front line where offensive linemen Blake Miller, Christian Mahogany, and Juice Scruggs are tending to ailments. Miller was designated as a non-participant, while Mahogany contends with a hip issue sustained during Detroit's Week 1 triumph over the New Orleans Saints.

Additionally, defensive back Avonte Maddox could potentially sit out the midweek showdown against quarterback Josh Allen.